Please use this identifier to cite or link to this item:
http://hdl.handle.net/20.500.11889/8374
Title: | Synthesis of nitro- And aminoisoflavones and their effects on the proliferation of endothelial cells | Authors: | Al-Maharik, Nawaf Jaradat, Nidal Hidmi, Adel |
Keywords: | Nitroisoflavone;Aminoisoflavone;Isoflavones;Endothelial Cells | Issue Date: | 2020 | Publisher: | Journal of the Chemical Society of Pakistan | Abstract: | The new nitroisofalvones 2a-k were synthesized via nitration of the corresponding isoflavones 1a-f using NH4NO3/TFAA in acetonitrile. The aminoisoflavones 3a-g, also new, were produced by selective reduction of the corresponding nitro isoflavones with SnCl2.2H2O. The nitro- and aminoisoflavones, tested in vitro concerning their effects on the proliferation of endothelial cells showed modest activities. All the new products are fully characterized and the nitro compounds analyzed thoroughly by NMR to allow complete assignment of the proton and carbon resonance and to establish the orientation of nitration. | URI: | http://hdl.handle.net/20.500.11889/8374 |
Appears in Collections: | Fulltext Publications |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Synthesis of nitro- And aminoisoflavones and their effects on the proliferation of endothelial cells.pdf | 700.85 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.