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Title: Prokaryotic and Mitochondrial Lipids: A Survey of Evolutionary Origins
Authors: Rappocciolo, Emilia 
Stiban, Johnny 
Keywords: Evolution;Membrane lipids;Mitochondria;Membrane lipids;Mitochondries;Prokaryotes;Sphingolipids
Issue Date: 2019
Abstract: Mitochondria and bacteria share a myriad of properties since it is believed that the powerhouses of the eukaryotic cell have evolved from a prokaryotic origin. Ribosomal RNA sequences, DNA architecture and metabolism are strikingly similar in these two entities. Proteins and nucleic acids have been a hallmark for comparison between mitochondria and prokaryotes. In this chapter, similarities (and differences) between mitochondrial and prokaryotic membranes are addressed with a focus on structure-function relationship of different lipid classes. In order to be suitable for the theme of the book, a special emphasis is reserved to the effects of bioactive sphingolipids, mainly ceramide, on mitochondrial membranes and their roles in initiating programmed cell death.
ISSN: 0065-2598
Appears in Collections:Fulltext Publications

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