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Title: Time-related changes in hepatic and colonic mitochondrial oxygen consumption after abdominal infection in rats
Authors: Herminghaus, Anna 
Papenbrock, Henrike 
Eberhardt, Rebecca 
Vollmer, Christian 
Truse, Richard 
Schulz, Jan 
Bauer, Inge 
Weidinger, Adelheid 
Kozlov, Andrey V 
Stiban, Johnny 
Picker, Olaf 
Keywords: Abdominal infection;Abdomen - Diseases;Colon - Infection;Liver - Infection;Cellules - Respiration;Mitochondries;Mitochondria;Time course;Infectious diseases;Sepsis
Issue Date: 8-Jan-2019
Abstract: Evidence suggests that early adaptive responses of hepatic mitochondria occur in experimentally induced sepsis. Little is known about both colonic mitochondrial function during abdominal infection and long-term changes in mitochondrial function under inflammatory conditions. We hypothesize that hepatic and colonic mitochondrial oxygen consumption changes time-dependently after sterile laparotomy and in the course of abdominal infection. The aim of the present study was to investigate the hepatic and colonic mitochondrial respiration after sterile laparotomy and abdominal infection over up to 96 h.
ISSN: 2197-425X
Appears in Collections:Fulltext Publications

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