Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.11889/5901
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dc.contributor.authorRaymoni, Ghana-
dc.contributor.authorAbu Ali, Hijazi-
dc.date.accessioned2019-04-16T06:14:54Z-
dc.date.available2019-04-16T06:14:54Z-
dc.date.issued2019-01-01-
dc.identifier.urihttp://hdl.handle.net/20.500.11889/5901-
dc.description.abstractNovel Zn(II) complexes with the general formula: [Zn(furo)2(L)n], n = 1 or 2, (furo = furosemide = (4‐chloro‐2‐(furan‐2‐ylmethylamino)‐5‐sulfamoylbenzoic acid) were prepared. The complexes [Zn(furo)2(MeOH)2] (1; MeOH = methanol), [Zn(furo)2(2‐ampy)2] (2; 2‐ampy = 2‐aminopyridine), [Zn(furo)2(2‐ammepy)2] (3; 2‐ammepy = 2‐aminomethylpyridine), [Zn(furo)2(H2O)(2,2‐bipy)] (4; 2,2′‐ bipy = 2,2′‐bipyridine), [Zn(furo)2(H2O)(4,4′‐bipy)] (5; 4,4′‐bipy = 4,4′‐ bipyridine), [Zn(furo)2(1,10‐phen)] (6; 1,10‐phen = 1,10‐phenanthroline), [Zn(furo)2(2,9‐dmp)] (7; 2,9‐dmp = 2,9‐dimethyl‐1,10‐phenanthroline), and [Zn (furo)2(quin)2] (8; quin = quinoline) were synthesized and characterized using different techniques such as IR, UV–Vis, 1 H NMR, 13C NMR, LC/MS and others. The crystal structure of complex (4) was determined using single‐ crystal X‐ray diffraction. The anti‐bacterial activity of complexes (1–8) was tested using agar diffusion method against three gram‐positive (Staphylococcus aureus, Bacillus subtilis and Staphylococcus epidermidis) and three gram‐negative bacteria (Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa). The obtained results showed different Inhibition Zone Diameters (IZD) with various anti‐bacterial activities against the selected gram‐positive and gram‐negative bacteria. In addition, the rate of bis‐(4‐nitrophenyl) phosphate hydrolysis was measured at different temperatures, different pH values and different concentrations. The rates for the eight complexes were in the following order: complex 4>2>5>8 > 7 > 6 > 3 > 1.en_US
dc.language.isoen_USen_US
dc.publisherWILEYen_US
dc.subjectAnti‐bacterial activityen_US
dc.subjectBioactive nitrogen based ligandsen_US
dc.subjectBis‐(4‐nitrophenyl) phosphaten_US
dc.subjectFurosemideen_US
dc.subjectZinc (II) complexesen_US
dc.titleSynthesis, Structures and Various Biological Applications of New Zn(II) Complexes Having Different Coordination Modes Controlled by the Drug Furosemide in Presence of Bioactive Nitrogen Based Ligands.en_US
dc.typeArticleen_US
newfileds.departmentScienceen_US
newfileds.corporate-authorAbu Ali, Hijazien_US
newfileds.item-access-typeopen_accessen_US
newfileds.thesis-prognoneen_US
newfileds.general-subjectNatural Sciences | العلوم الطبيعيةen_US
item.languageiso639-1other-
item.fulltextWith Fulltext-
item.grantfulltextopen-
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