Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.11889/5700
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dc.contributor.authorBatrawi, Nidal
dc.contributor.authorAl-Rimawi, Fuad
dc.contributor.authorQurt, Moammal S.
dc.contributor.authorNaseef, Hani
dc.date.accessioned2018-11-08T07:58:25Z
dc.date.available2018-11-08T07:58:25Z
dc.date.issued2018-10-30
dc.identifier.citationhttp://globalresearchonline.net/journalcontents/v52-2/07.pdfen_US
dc.identifier.issn0976 – 044X
dc.identifier.urihttp://hdl.handle.net/20.500.11889/5700
dc.descriptionAn article published in : International Journal of Pharmaceutical Sciences Review and Research, 52(2), September-October 2018 ; Article No. 07, Pages: 39-43
dc.description.abstractParenteral dosage forms are one of the most commonly used pharmaceutical dosage forms in veterinary medicine, at the same time the combination therapy of multiple drug products is a common practice in this field. The aim of this research was to develop a high quality, stable solution that combines Florfenicol and Flunixin meglumine in a multidose injectable dosage form. Different organic solvents were tested to determine the optimal solvent for the active substances in the formulation. Citric acid was used in the formulation to overcome the problem of Flunixin instability and ethyl alcohol was incorporated in the formula in order to enhance syringeability and injectability of the solution. All prepared formulations were evaluated for their chemical and physical stabilities. The candidate formula showed good physical and chemical stability after two weeks of storage at both room temperature and accelerated conditions. Samples from three pilot scale batches were stored at accelerated stability conditions for 6 months and didn’t show any significant physical or chemical instability. A generic parenteral solution drug product containing Florfenicol and Flunixin meglumine for veterinary use was successfully developed using mixture of organic solvents and excipientsen_US
dc.description.sponsorshipAdvanced Veterinary Manufacturing Company (Palestine)en_US
dc.language.isoen_USen_US
dc.publisherGlobal research onlineen_US
dc.subjectAnti-infective agents in veterinary medicineen_US
dc.subjectNonsteroidal anti-inflammatory agentsen_US
dc.subjectVeterinary chemotherapyen_US
dc.subject.lcshMedicine - Formulae, receipts, prescriptions
dc.subject.lcshVeterinary medicine
dc.subject.lcshParenteral solutions
dc.subject.otherFlorfenicol
dc.subject.otherFlunixin
dc.subject.otherThiamphenicol
dc.subject.otherResflor Gold
dc.titleDevelopment and evaluation of parenteral solution containing florfenicol and flunixin meglumine for veterinary useen_US
dc.typeArticleen_US
newfileds.departmentPharmacy - Nursing and Health Professionsen_US
newfileds.custom-issue-date2018en_US
newfileds.item-access-typebzuen_US
newfileds.thesis-prognoneen_US
newfileds.general-subjectHuman Biology, Medicine and Health Sciences | الطب والعلوم الطبيةen_US
item.languageiso639-1other-
item.fulltextWith Fulltext-
item.grantfulltextopen-
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