Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.11889/4817
Title: Sulfasalazine matrix coating with low mw DLPOLY (Lactic Acid)
Authors: Shtaya, Hani
Keywords: Miblemman method
Vivo and in Vitro studies
Spectrophotometer
Issue Date: 2003
Abstract: 11th Panhellenic Pharmaceutical Congress 65 enhancer (M). The results were described by in vivo and in vitro studies. In vitro we used the Miblemman method and in vivo we used groups of 6 eats with weight near 120:1:10g. The contained in MET was counted on spectrophotometer UVN1S Jasco V530 at 15, 30, 60, 90 min. (A=257nm for MET) (2). The three formulas of suppositoria met the conditions of F.R.X concerning aspect, mass uniformity, melting characteristics and cantitative dosage..The kinetics of release and difuthion of sodium metamizole displayed.no significant differences between S and C formulas. The T formula had better results also in vitro and in viva In conclusion, the quantity of sodium metamizole which penetrated the biological membrane was higher when associating the penetration enhances for formulation T (90%), compared to standard sample M (79%).
URI: http://hdl.handle.net/20.500.11889/4817
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