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Title: Acylated flavone O-glucuronides from the aerial parts of nepeta curviflora
Authors: Rabee, Maysaa 
Andersen, Øyvind Moksheim 
Fossen, Torgils 
Enerstvedt, Kjersti Hasle 
Abu Ali, Hijazi 
Rayyan, Saleh 
Keywords: Catnip, Syrian;Nepeta curviflora;Lamiaceae;Aecylated flavone;7-O-glucuronosides
Issue Date: 2020
Publisher: Molecules
Abstract: Nepeta curviflora Boiss. (Syrian catnip) is native to the Middle East. This medicinal plant is commonly used against nervous disorders, rheumatic pains, and high blood pressure. Herbal infusions prepared from various Nepeta spp. are extensively consumed as functional food. However, limited information has been known about the phenolic constituents of Syrian catnip. In this study, two acylated flavone 7-O-glucuronides, apigenin 7-O-(2”-O- (2000-(E-ca eoyl)- -glucuronopyranosyl)- -glucuronopyranoside) (1) and luteolin 7-O-(2”-O-(2000- (E-ca eoyl)- -glucuronopyranosyl)- -glucuronopyranoside) (2), along with the known phenolic compounds rosmarinic acid, ca eic acid, apigenin, and apigenin 7-O- -glucopyranoside were isolated from the aerial parts of N. curviflora. The characterizations of these compounds were based on high-resolution mass spectrometry, UV, and extensive use of multidimensional NMR spectroscopy. The new compounds (1 and 2) were identified in the unmodified state and as dimethylesters.
DOI: 10.3390/molecules25173782
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