Please use this identifier to cite or link to this item:
http://hdl.handle.net/20.500.11889/2136
DC Field | Value | Language |
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dc.contributor.author | Hamed, Mazen | - |
dc.contributor.author | Neilands, J. B. | - |
dc.contributor.author | Huynh, V. | - |
dc.date.accessioned | 2016-10-08T06:45:17Z | - |
dc.date.available | 2016-10-08T06:45:17Z | - |
dc.date.issued | 1993-5 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11889/2136 | - |
dc.description | Article published in : Journal of Inorganic Biochemistry. 1993 May 15;50(3):193-210 | - |
dc.description.abstract | The binding of the repressor protein (Fur) to Fe(H) as co-repressor was studied. Other transition metal ions such as M&I), Co(B), and Cu(I1) were also studied as models. From the equilibrium studies Kd values of 55,85,36, and 10 PM were obtained for the Fur complex with Fe(II), Mn(II), Co(II), and C&I), respectively. The ratio of metal to Fur monomer was 1:l in both the Fe(II) and M&I) complexes. Fur mutants were also studied. Electronic absorption spectra of the CofII) Fur complex gave evidence of a distorted tetrahedral Co(E) site bound to sulfur. Frozen solution 57Fe Miissbauer spectra of the Fe(B) Fur indicated the presence of Fe(II) in a high spin distorted octahedral environment. The role of the metal ion as co-repressor in the binding of Fur to DNA is discussed in view of the above results. | - |
dc.language.iso | en | en_US |
dc.publisher | ResearchGate | en_US |
dc.subject.lcsh | Metal bonding | - |
dc.subject.lcsh | Transition metal ions | - |
dc.subject.lcsh | Metals - Spectra | - |
dc.subject.lcsh | DNA-binding proteins | - |
dc.title | Binding of the ferric uptake regulation repressor protein (Fur) to Mn(II), Fe(II), Co(II), and Cu(II) ions as co-repressors : electronic absorption, equilibrium, and 57Fe Mossbauer studies | en_US |
dc.type | Article | en_US |
newfileds.department | Department of Chemistry | en_US |
newfileds.item-access-type | open_access | en_US |
item.languageiso639-1 | other | - |
item.fulltext | With Fulltext | - |
item.grantfulltext | open | - |
Appears in Collections: | Fulltext Publications |
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File | Description | Size | Format | |
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Binding of the ferric uptake regulation repressor protein.pdf | 1.09 MB | Adobe PDF | View/Open |
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